aantal |
item |
Beskrywing |
2 |
Vaartuigstelsel |
Autoclavable bioreactor vessel,5L (3 - 3.5 liters working volume) and 7 liter (4-5 liters working volume) and 10 liter (5-7 liters working volume)total capacity Lid Stainless steel 316L With sterile and pressure proof ports bioreactor Vessel must be a Jacketed Vessel having with the head plate of SS316L. It should have the Temperature Control via circulation of Hot / Cold Water in the Jacket through an inbuilt Thermo circulator unit (working temperature range 8ºC - 80ºC above coolant temperature) The system must be complete to measure and control pH, DO, stirrer speed (20-300rpm), foam control & temperature. Probes : Impeller Speed, temperature, pH, redox, pO2, level or Foam, gas mixture Gas Supplement : Air, O2, N2, CO2 geroer Mechanical seal, shaft, 2 height adjustable six – blade stirrer, removable baffle cage deurlugting Auto cleavable sterile filter, check valve, connection piece, aeration tube with ring sparger Required air pressure approx, 1.5 bar ventilasie Reflux cooler, connection piece, auto cleavable sterile filter Temperature Circuit Connected to glass double jackets, all four temperature circuits connected by central supply and drain lines. probes Autoclavable temperature probe Pt100 incl. connecting cable Autoclavable pH-gel-electrode incl. connecting cable Autoclavable pO2-probe incl. connecting cable Autoclavable height adjustable antifoam-probe incl. connecting cable Monsternemingstelsel Autoclavable sampling system inokulum Cup for silicone diaphragm Measurement of Controls Integrated in stainless steel trunking Kragtoevoer Main power supply for all electrical circuits, 1 x 220V, 50 Hz Temperatuur beheer Including heating finger and cooling water valve in temperature circuit. Temperature controller for heating and cooling, temperature range 4-60C (depending on the available cooling media) Spoedinstelling DC motor with frequency converter, rpm-control unit pH Control pH-control to activate the dosage of acid and base (pumps) pO2 Control DDC pO2-control to activate the final elements, Cascade control vial stirrer speed and aeration valve Antifoam Control DDC antifoam - Control to activate the dosage to antifoam chemicals Dosis Aeration Unit Consists of pressure valve, a rotameter (50-100L/h) a continuous solenoid valve (proportional valve), activated by pO2 controller, a check valve. Peristaltic Pump with variable speed |
2 |
Aeration system |
Include rotameter, aeration filter |
2 |
Agitation system |
GJ:Meganiese sealing system at the top of the fermenter; high-powered stirring oar, antifoam oar; AC elektriese masjien: infinite speed variation; rpm in the 5L germ fermenter: 20~300rpm±1%,The height of the stirring oar can be adjusted, too. |
2 |
Temperatuurbeheer |
Interlayer electric calefaction, auto-control |
2 |
lugvloei beheer |
Provision for mixing at least four gases (Air, Oxygen, Nitrogen and CO2), Thermal mass flowmeter automatic control gas flow, valves, gas mix station to be included. Air filtration with membrane filter Supply capacity for fermenter: Air: upto 2 VVM, Oxygen ≥ 0.5 VVM, Sparger - One number sparger. |
2 |
Antifoam beheer |
Automatically check foam, automatically add antifoam by peristaltic pump. |
2 |
Feeding control |
Control by peristaltic pump switch, automatically feeding and computation. |
2 |
pH control |
Automatically add acid, alkali by peristaltic pump and control pH accurately. |
2 |
DO control |
Control with rotating speed relatively. |
1 |
BIO-S Biology process controller |
Control parameter: temp, pH, DO, antifoam, stirrer rev, feeding; (Other parameters like glucose, amino acid, ethanol, oxygen, carbon dioxide, electric balance system can be chosen to use.) |
Beheer stelsel |
BLBIO B Control System: on-site controller, the next crew for the Siemens S7-200 series PLC control system, it is a mature, stable, universal type of PLC, to suit a variety of automation applications, especially in manufacturing process control Application. Its modular, easy to implement distributed configuration and easy to master and so on, Siemens PLC control center has become a biological reaction process control implementation is economical and advanced control system, the system uses the touch screen display, on-site direct operations (menu type), all English menu and interface; also with the host computer for data transmission, data sampling and display tank, the system view of data analysis, reading settings. 10-inch LCD touch-sensitive screen as the display screen to display complete content-rich, user-friendly screen is simple, easy to operate. And disturbing each other. The control system can adapt to different range of sensors and actuators the output of the input signal with the signal anti-jamming system. Sagteware: Siemens S7 + FORCE CONTORL Data collection and control module: Siemens S200 PLC controller and data collection and control module 1. beheer
2. Measurement function: can feeding, bubble enemy, such as measurement of pH 4. Data verwerking
5) data storage format is compatible with EXCEL, EXCEL platform can be to deal with 9. show the controller is really running against, the panel instructed the state process system, process hardware, and motion status indicator for understanding the various devices (such as peristaltic pumps, circulating pumps, heating, mixing, etc.) work status, Fault identification can be used as display |
Tegniese parameter:
Geen |
Parameter |
riglyn |
Controller data processing function |
1 |
PH |
Displaying range: 0.00 ~ 14.00 ± 0.01 Auto-control range:2.00 ~ 12.00 ± 0.05 Fermentation proses beheer (According to the fermentation time, auto- control pH fluent, at least10 parts) |
pH value historical and trend curve analysis Acid, alkali dosage curve analysis Batch report form analysis Acid, alkali total dosage record Keep and deliver data |
2
|
DO
|
0-150±3%,vertoon precision: 0.1% It can be controlled by rev and feeding. Fermentation proses beheer (According to the fermentation time, auto- control DO fluent, at least10 parts) |
DO value historical and trend curve analysis Batch report form analysis Keep and deliver data |
3
|
antifoam |
Outomatiese PID control and alarm Fermentation proses beheer (According to the fermentation time, auto- control antifoam fluent, at least10 parts) |
Antifoam value historical and trend curve analysis Foam error state record antifoam total dosage record Batch report form analysis Keep and deliver data |
4
|
Ds |
Outomatiese enactment en beheer(50~300rpm±5‰) Fermentation proses beheer (According to the fermentation time, auto- control rev fluent, at least10 parts) |
Rev value historical and trend curve analysis Batch report form analysis Keep and deliver data |
5 |
temperatuur |
Temperature of cooling water: +5℃-80℃± 0.2 ℃ Fermentation proses beheer (According to the fermentation time, auto- control temperature fluent, at least10 parts) |
Temperature value historical and trend curve analysis Batch report form analysis Keep and deliver data |
6
|
Voeding |
PID automatic enactment en beheer Fermentation proses beheer (According to the fermentation time, auto- control feeding fluent, at least10 parts) |
Feeding value historical and trend curve analysis Feeding total dosage record Batch report form analysis Keep and deliver data |
7
|
Druk |
Manual control, instrument display |
|
8
|
Air flux |
mass flowmeter control gas flow |
|
System main parts
item |
Produk |
Beskrywing |
Quant. |
Bron |
1 |
tank |
GJ, GC: stainless steel cover, Borosilicate glass tank, stainless steel round jacketed bottom and 5mm stainless steel jacketed tank, control temperature together, heating by bottom verwarming kombers. |
1 |
Bailun |
2 |
Machinery seal |
John Crane |
1 |
Verenigde Koninkryk |
3 |
Roer motor |
Mechanical stirring: TECO |
1 |
TECO |
4 |
Spoedbestuurder |
Mechanical stirring: TECO |
1 |
TECO |
5 |
Silicon pipe |
Lange |
10M |
Baoding |
6 |
PLS-stelsel |
Germany Siemens S7-200 series PLC control system +10 inch Kunlun-type LCD touch screen + circuit control board + electrical boxes and various types of electrical appliances. Including cabinets, control core, signal acquisition, transmitter, power drive and other types of actuators |
1 |
Bailun |
7 |
Termiese massa vloeimeter |
10-100L/H Vogtlin |
1 |
Switserland |
8 |
Air intake filter |
Sartorius, 0.2μm φ50 |
1 |
Sartorius |
9 |
Asemhalingsfilter |
Sartorius φ37 |
1 |
Sartorius |
10 |
Feeding peristaltic pump |
BL-0~32 ml\min |
1 |
Lange |
11 |
Peristaltic pump(acid) |
BL-0~28 ml\min |
1 |
Lange |
12 |
Peristaltic pump(Alkali) |
BL-0~28 ml\min |
1 |
Lange |
13 |
Peristaltic pump(Defoaming) |
BL-0~28 ml\min |
1 |
Lange |
14 |
PH electrode |
Switzerland imported 225 |
1 |
Switserland |
15 |
PH cable |
Switzerland imported 3m |
1 |
Switserland |
16 |
DO electrode |
Switzerland imported 220 |
1 |
Switserland |
17 |
DO cable |
Switzerland imported 3m |
1 |
Switserland |
18 |
Temperature electrode |
PT100 |
1 |
Japan |
19 |
Elektromagnetiese klep |
DN8-UNIT |
1 |
Taiwan |
20 |
ander |
Feeding bottle, silicone tube, pipe, pipe rack, all kinds of valves, heaters, pressure gauges, bearings, seals, tools, etc. |
1 |
Sjanghai |
vaccine production plant |
vaccine production line manufacturing |
Pharmaceutical fermentation |
Biofarmaseutiese bioreaktor |
apteek |
farmaseutiese produkte |
medisyne |
Monoklonale teenliggaampies |
Antibiotika |
antibiotika |
Animal cells cultivation |
animal cells suspension cultivation |
veterinary medicine stirring tank |
Entstof |
biofarmaseutiese |
menslike selle |
plant cell culture |