Stainless steel bioreactors-fermentors

12-In-Situ Sterilizable Bioreactors 500 liter

Bacteria Fermenter with double mechanical Seal at bottom

  • Description
  • Competitive & Advantage
  • Inquiry

Fermentor|bioreactor(500Liters ,Mechanical sealing system at the bootom of the fermenter;Double mechanical Seal) Model: KNIKBIO -500SBA
Total volume:500 liters
Working volume: 150L -400 liters
Material: 316L stainless steel with material contact to the other 304 stainless steel
Sterilization method: Manual situ sterilization(SIP  options)
Control system: Siemens PLC, industrial LCD touch computer control, parameters can be set to store, can be remotely connected to the computer through the USB interface, the data
Working volume 250 to 400 liters and The main material of the fermenter is made by 316Lstainless steel. The design pressure: P(inside)= 0.3Mpa, P(interlayer)= 0.3Mpa, The polishing precision: Ra0.4~0.6, the ratio between diameter and height: 1:2.6

Stirring system

Mechanical sealing system at the top of the fermenter; high-powered stirring oar, antifoam oar; AC electrical machine: infinite speed variation; rpm in the fermenter: 70~500rpm±1%,The height of the stirring oar can be adjusted, too.
Temperature detection and control
Heat by thermostatic water tank and circulate by circulating pump(Grundfos, Denmark), autocontrol (cooling water+5℃)~65℃±0.1℃,temperature probe(US)
pH detection and control
2.00-12.00±0.05pH, autocontrol by adding acid and base, pH sensor (Mettler, Switzerland) and shielding lead (Mettler, Switzerland). fermenter is autocontrolled with peristaltic pump
DO detection and control
0-150±3% displaying precision 0.1%, sensor (Mettler, Switzerland) and shielding lead(Mettler, Switzerland)
Feed control
fermenter uses peristaltic pump (Longer) to add meterials
Antifoam control
Tested by sencor and added antifoamer by peristaltic pump
Intake control (air): manual control rotameter
pressure detection and control
Pressure Control: Pressure meter and digital display and digital remote control, pressure control
we are compliant fermentation equipment for research, development, pilot and production applications. Our Factory in China. We provide the fermentor products including : Stainless steel  fermenter, Pilot combo stainless steel fermentor, glass fermentor,  fermenter, Multi-Union fermenter,Multi-stagefermentation tank,and shaking Incubators ,  Positive join stainless steel fermentor.

Competitive Advantage

Technical parameter:
Material and brand of key components


Key component

Material and brand


Vessel system

The cylinder designed by our company uses stainless steel


Speed Motor



Speed regulator

Fuji, Japan


Solenoid valve



Aeration filter

0.2μm, Dominica United Kingdom


Breathing filter

0.2μm, SARTORIUS, Germany


pH electrode

Hamilton /Mettler-Toledo, Switzerland


DO electrode

Hamilton /Mettler-Toledo, Switzerland


Peristaltic pump

Lange (United States)



Siemens Germany


LCD touch screen



Mechanical seal

John Crane United Kingdom

1. Double end face and cooling lubricaton system        7. Double mechanical seal - Double protection
2. Inactivated exhaust system                                      8. Pressure regulator
3. Effect of stirring                                                         9. Balance feeding weighing system
4. Thermal mass flowmeter                                           10. Tank weighing module-mettler
5. Tank cap automatically open system                         11. Siemens PLC, schneider intermediate
6. Tank bottom feeding and moving system                  12. All kinds of impeller

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